reuptake

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re·up·take

(rē-ŭp′tāk′)

The reabsorption of a neurotransmitter, such as serotonin or norepinephrine, by a neuron following impulse transmission across a synapse.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

reuptake

(riːˈʌpteɪk) biochem

vb (tr)

to reabsorb (a neurotransmitter) following the transmission of a nerve impulse across a synapse

the reabsorption of a neurotransmitter by a neuron following the transmission of a nerve impulse across a synapse

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

re•up•take

(riˈʌpˌteɪk)
n.

the reabsorption of a chemical into the cell that released it.

[1975-80]

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Noun

reuptake - a process of using up or consuming again; "psychopharmacologists discovered that amine reuptake is a process that inactivates monoamine neurotransmitters"

re-uptake

uptake - a process of taking up or using up or consuming; "they developed paper napkins with a greater uptake of liquids"

References in periodicals archive ?

In a case-control study of all patients admitted with gastrointestinal bleeding to three hospitals over an 18-month period, 17% of the 417 patients with bleeding were using a selective serotonin reuptake inhibitor (SSRI) at the time.

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An analysis of data from a large, federally funded clinical trial indicates that when such patients take antidepressant medication of the class known as selective serotonin reuptake inhibitors (SSRIs), they reap major heart-health benefits.

Heartening responses: depression drugs may aid survival after heart attack

In addition, a double-blind, placebo-controlled pilot study showed rapid efficacy of ALKS 5461 in 32 patients with major depressive disorder who failed to respond adequately to treatment with selective serotonin reuptake inhibitors (SSRIs) or selective serotonin-norepinephrine reuptake inhibitors (SNRIs), he said.

Drug channels 'opium cure' for depression

AstraZeneca has been collaborating with Targacept Inc (Nasdaq:TRGT) on the global development of TC-5214, with the initial goal being to develop the drug as an adjunct treatment for major depressive disorder (MDD) in patients with an inadequate response to a selective serotonin reuptake inhibitor (SSRI) or serotonin/norepinephrine reuptake inhibitor (SNRI).

AstraZeneca and Targacept abandon plans for antidepressant TC-5214

In 2005, the Food and Drug Administration rejected the short-acting selective serotonin reuptake inhibitor for use in the United States.

Thinking about baseball passe, says J&J

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-- The fear that combining migraine medication with selective serotonin reuptake inhibitors can increase the risk of serotonin syndrome may be over-stated, Dr.

SSRIs plus migraine medications: few data for serotonin syndrome precaution

7 December 2010 - US biotechnology company Genentech Inc, a member of Swiss drugmaker Roche Group (VTX: ROG) announced on Sunday eight-week results from a Phase II study of RG16781, its investigational first-in-class glycine reuptake inhibitor (GRI) for the treatment of schizophrenia, which showed meaningful impact on the negative symptoms of disease.

Genentech's RG16781 shows positive impact on schizophrenia negative symptoms

VIENNA -- An estimated 700,000 Americans were at risk for serotonin syndrome in 2004 because they were simultaneously on a triptan and a selective serotonin reuptake inhibitor or serotonin-norepinephrine reuptake inhibitor, according to data reported at the annual congress of the European College of Neuropsychopharmacology.

Many migraine patients at risk for serotonin syndrome

On average, about 61% of patients will experience at least one side effect from taking a selective serotonin reuptake inhibitor (SSRI) or a serotonin norepinephrine reuptake inhibitor (SNRI), according to the analysis.

Antidepressant side effects vary

Researchers now report that popular antidepressants called selective serotonin reuptake inhibitors (SSRIs) might diminish the effectiveness of tamoxifen by limiting its conversion into medicinally important agents.

Bad combo? Some antidepressants may hamper breast cancer drug

SAN FRANCISCO -- The serotonin-norepinephrine reuptake inhibitor venlafaxine is as effective as paroxetine in the treatment of panic disorder, Dr.

Venlafaxine XR matches paroxetine for panic disorder: equal efficacy, tolerability