opsonin

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op·so·nin

(ŏp′sə-nĭn)

A substance, such as an antibody or complement protein, that binds to a bacterium or other pathogen and causes it to become more susceptible to the action of phagocytes.

[Latin opsōnāre, to buy provisions (from Greek opsōnein, from opson, condiment, delicacy; see epi in Indo-European roots) + -in.]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

opsonin

(ˈɒpsənɪn)

(Biochemistry) a constituent of blood serum that renders invading bacteria more susceptible to ingestion by phagocytes in the serum

[C20: from Greek opsōnion victuals]

opsonic adj

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

op•so•nin

(ˈɒp sə nɪn)

n.

any of several constituents of blood serum, as an antibody or complement, that make invading microorganisms more susceptible to destruction by phagocytes.

[1900–05; < Latin opsōn(ium) victuals]

op•son•ic (ɒpˈsɒn ɪk) adj.

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Noun

opsonin - an antibody in blood serum that attaches to invading microorganisms and other antigens to make them more susceptible to the action of phagocytes

blood serum, serum - an amber, watery fluid, rich in proteins, that separates out when blood coagulates

antibody - any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response

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opsonina

op·so·nin

n. opsonina, anticuerpo que al combinarse con un antígeno hace que éste sea más suceptible a los fagocitos.

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References in periodicals archive ?

However, covalent binding method has been found to rule over the adsorption method since in vivo opsonins may compete with the adsorbed molecules onto NP surface.

Targeted Therapeutic Nanoparticles: An Immense Promise to Fight against Cancer

The presence of polyethylene glycol (PEG) on the surface of liposomes provides a steric barrier against opsonins that reduces the uptake of liposomes by the MPS cells [13, 14] and thus allows their uptake by other cells.

Accelerated Blood Clearance (ABC) Phenomenon Favors the Accumulation of Tartar Emetic in Pegylated Liposomes in BALB/c Mice Liver

Many acute-phase proteins such as CRP and SAA, bind to microbial cell walls and they may act as opsonins and fix complement.

Study on post-operative infections with Teicoplanin prophylaxis in total knee arthroplasty

This bacterium inhibits the chemotaxis of neutrophils, suppresses the opsonins (both complement and immunoglobulin) and phagocytes, could rapidly react to abrupt changes in ROS (Lavoie et al., 2011; Laarman et al., 2012).

EFFECTS OF FEVERFEW (TANACETUM PARTHENIUM) AND ANTIBIOTIC CO-ADMINISTRATION ON BLOOD NEUTROPHIL FUNCTION AND SERUM PROCALCITONIN IN DOGS WITH EXPERIMENTAL SUBCUTANEOUS PSEUDOMONAS AERUGINOSA INFECTION

The activation proceeds as an enzyme cascade with proteins acting as cofactors for each other thus generating opsonins for enhanced cellular recognition (C3b), anaphylatoxins that drive local inflammation (C3a and C5a), and terminally the membrane-attack complex (C5b-9) that mediates cell lysis.