nuclein


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Related to nuclein: nucleic acid, Chargaff

nu·cle·in

 (no͞o′klē-ĭn, nyo͞o′-)
n.
Material from the nucleus of a cell, considered a single substance when first isolated in the late 1800s but later shown to consist of DNA and associated proteins.

nu′cle·in′ic adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

nuclein

(ˈnjuːklɪɪn)
n
(Biochemistry) any of a group of proteins, containing phosphorus, that occur in the nuclei of living cells
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
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While delving microscopically through the pus in surgical bandages, Miescher found a substance he didn't recognize and called it nuclein (because it resided in the nuclei of cells).
Since 1869 when Johann Frierich Miescher first discovered nucleic acid (which he called "nuclein") the study of genetics, and more recently, genomics, has been at the forefront of medical research.
Early isolation of NA, originally called nuclein, was performed using tedious methods to isolate pure material.

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