alloxan


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Related to alloxan: streptozotocin

alloxan

(əˈlɒksən)
n
a reddish organic compound C4H2N2O4 produced by oxidation of uric acid
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
References in periodicals archive ?
The results obtained when alloxan induced rats were treated with C.
Effect of figs fruit (Ficus carica L.) and its leaves on hyper-glycemia in alloxan diabetic rats.
Ethanol extract (70 %) of the whole plant was evaluated for anti-diabetic activity in mice that were induced by alloxan. The plant showed a lowering effect of blood glucose at a significant level (303.86 +- 11.71 mg/dl) by comparing with hyperglycemic untreated group (521.57 +- 17.84 mg/dl).
Diabetes Induction in mice: Alloxan monohydrate (C4H2N2O4.H2O) was purchased from AppliChem GmbH, Germany and used for diabetes induction.
Drugs causing methaemoglobinaemia are acetanilide, alloxan, aniline, arsine, benzene derivatives, bivalent copper, bismuth, bupivacaine, chorates, chloroquine, chromates, dapsone, dimethyl sulfoxide, dinitrophenol, exhaust fumes, ferricyanide, flutamide, hydroxylamine, lidocaine, metoclopramide, naphthalene, nitrates, nitrofuran, nitroglycerin, sodium nitroprusside, paraquet, phenacetin, phenol, phenytoin, rifampin, sulphasalazine and sulphonamides
All groups of animals induced with alloxan 200 mg/kgBW except Group 1 (normal control) with intraperitoneal on day 0, followed by animal testing from day 1-day 24.[11] Test preparations were administered to each treatment group mice for 24 days orally.
Mice were intravenously administrated a single dose of 70 mg/kg of alloxan (Sigma-Aldrich, USA) dissolved in ISS (15).
Effect of figs fruit (Ficus carica L.) and its leaves on hyperglycemia in alloxan diabetic rats.
Araujo, Braga & Medeiros (17) induced diabetes mellitus by alloxan in 27 male Wistar rats, equally distributed in three groups.
Except for the rats in group 1 (control), DM was experimentally induced in the animals of groups 2-7, after fasting them overnight by intraperitoneal administration of alloxan monohydrate dissolved in normal saline (150mg/kg) [29].