Those included were in-patients aged at least 18 years who had no communication problem, were using any of the agents leading to oral mucositis (alkylating agents such as
busulfan, melphalan, cyclophosphamide that are used at high doses; antimetabolites such as methotrexate, 5-fluorouracil; antibiotics such as dactinomycin, adriamycin, bleomycin, and alkaloids such as vinblastine), and who had no oral mucositis and provided informed written consent.
cyclophosphamide,
busulfan, and/or radiation(XRT)), development of acute GVHD, and CMV reactivation were also considered risk factors for the development of HC.
Patients will undergo a conditioning regimen administration with
busulfan intravenously for four days to achieve myeloablation prior to the transplant.
Finally, the stem cells are infused back into the patient, who has received a low dose of the chemotherapy medication
busulfan to help the genetically corrected stem cells establish themselves in the bone marrow and begin producing new blood cells.
M2 EQUITYBITES-March 18, 2019-Pii partners with Athenex Pharmaceuticals, Sungen Pharma and Chemwerth to manufacture
Busulfan Injection
Global Banking News-March 18, 2019-Pii partners with Athenex Pharmaceuticals, Sungen Pharma and Chemwerth to manufacture
Busulfan Injection
SunGen Pharma announced the launch of
Busulfan injection, the second product launch through their joint venture Peterson Athenex with Athenex (ATNX).
Hasford score used as prognotic factor in the pre TKI era (
busulfan, interferon), but known to be beneficial as a predicting of TKI therapy response.
We concluded that previous chemotherapy with multiple agents, including high dose
busulfan and cyclophosphamide for stem cell transplant conditioning had led to premature ovarian failure causing her severe climacteric problems.
The most commonly used groups of cytostatics include: --alkylating agents that covalently bind with DNA and RNA forming adducts (cyclophosphamide, ifosfamide, chlorambucil,
busulfan, temozolomide, as well as platinum analogues such as cisplatin, carboplatin and oxaliplatin);
In the pre-engraftment period, diarrhea occurs mostly due to mucosal damage caused by the conditioning regimen, such as alkylating agents,
busulfan, and combination regimens or radiotherapy (7).
Food and Drug Administration has approved use of
Busulfan Injection, the company's therapeutic equivalent for Busulfex.